As I pulled the warm buns from the oven, a wave of nostalgia washed over me—reminding me of late-night drives through fast-food lanes for a satisfying bite of comfort. These Easy Hot Roast Beef Sandwiches with Cheddar Cheese Sauce are my homemade twist on that beloved fast-food classic. In only 15 minutes, you can whip up a delicious dinner that feels indulgent but is refreshingly simple. With layers of tender roast beef slathered in a creamy cheddar sauce, this recipe serves as a quick weeknight hero, perfect for those evenings when cooking feels like a chore. And if you want to take it a step further, the tangy horseradish mayo adds a delightful kick that’s sure to impress even the pickiest of eaters. Curious how to bring this comforting meal to your table? Let’s dive in!

Why are Hot Roast Beef Sandwiches a Must-Try?
Comforting Cravings: This recipe delivers all the warmth and nostalgia of your favorite fast food, right in your kitchen.
Quick Preparation: Ready in just 15 minutes, it’s perfect for busy weeknights or spontaneous gatherings.
Flavor Explosion: The creamy cheddar cheese sauce and zesty horseradish mayo create a delightful flavor profile that will leave you wanting more.
Versatile Options: Elevate your sandwich with sautéed onions or spicy jalapeños, or lighten things up with whole grain buns—customize to your heart’s content!
Crowd Pleaser: Ideal for family dinners or entertaining guests, these sandwiches satisfy all ages and eating preferences. For side ideas, check out our delicious curly fries or a fresh side salad!
Hot Roast Beef Sandwiches Ingredients
For the Cheese Sauce
• Creamy Horseradish – Adds a zesty kick; substitute with prepared horseradish or omit for a milder taste.
• Mayonnaise – Provides creaminess to the sauce; can use Greek yogurt for a healthier option.
• Shredded Mild Cheddar Cheese – The main flavor component; using block cheese ensures a smoother melt.
• Cornstarch – Thickens the cheese sauce; can be substituted with flour, but expect a different texture.
• Evaporated Milk – Creates a smooth cheese sauce; substitute with whole milk or heavy cream for a richer taste.
• Butter – Adds richness when warming the roast beef; olive oil can be used for a lighter option.
For the Sandwich
• Thin-sliced Deli Roast Beef – The main protein; leftover roast beef can easily be used.
• Hamburger Buns – Serves as the sandwich base; can be replaced with hoagie rolls or whole-grain bread.
Indulge in these hot roast beef sandwiches, and let each bite transport you back to carefree evenings filled with delicious fast food favorites!
Step‑by‑Step Instructions for Easy Hot Roast Beef Sandwiches with Cheddar Cheese Sauce
Step 1: Prepare the Horseradish Mayo
In a small bowl, combine creamy horseradish with mayonnaise, mixing thoroughly until smooth. This zesty spread will elevate your sandwiches, adding a delightful kick. Set the mixture aside while you prepare the rest of your ingredients, ensuring that it’s ready to enhance your hot roast beef sandwiches once assembled.
Step 2: Make the Cheddar Cheese Sauce
In another bowl, toss the shredded mild cheddar cheese with cornstarch, ensuring every piece is coated. Gradually whisk in the evaporated milk, creating a smooth mixture. Transfer this blend to a microwave-safe bowl and heat it for about 1 minute, stirring halfway through. Once melted and creamy, this sauce will be the perfect complement to your sandwiches.
Step 3: Warm the Roast Beef
Heat a skillet over medium heat and melt the butter until it bubbles gently. Add the thin-sliced deli roast beef to the skillet, warming it thoroughly for about 2-3 minutes. The beef should be steaming but not overcooked. This step ensures your hot roast beef sandwiches are deliciously warm and ready to be layered with flavors.
Step 4: Assemble the Sandwiches
Take the bottom halves of your hamburger buns and generously spread the prepared horseradish mayo on each one. Layer the warm roast beef evenly atop the mayonnaise, allowing the savory flavor to shine through. This tasty foundation will make your hot roast beef sandwiches truly irresistible.
Step 5: Add the Cheddar Cheese Sauce
Spoon the creamy cheddar cheese sauce over the stacked roast beef, letting it flow over the edges for that indulgent look and taste. The gooey texture brings the flavors together beautifully, making your sandwiches a feast for the eyes as well as the palate. Finally, crown each sandwich with the top bun for a complete creation.
Step 6: Serve and Enjoy
Serve your hot roast beef sandwiches immediately, allowing the warmth to envelop each layer. As they emerge steaming from your kitchen, consider pairing them with crispy curly fries or a fresh side salad to round out your meal. Enjoy every savory bite of this comforting favorite made right at home!

Make Ahead Options
These Easy Hot Roast Beef Sandwiches with Cheddar Cheese Sauce are perfect for meal prep enthusiasts! You can prepare the horseradish mayo and cheese sauce up to 24 hours in advance, allowing the flavors to meld. Simply refrigerate them in airtight containers. Additionally, you can warm the roast beef and store it separately for up to 3 days in the fridge; just reheat it gently before assembling. When you’re ready to serve, spread the mayo on the buns, layer the warm beef, drizzle with the cheese sauce, and top with the other bun. This way, you’ll have a delicious meal ready in minutes, perfect for busy weeknights!
What to Serve with Easy Hot Roast Beef Sandwiches
Pairing these delectable sandwiches with the right sides makes for a truly satisfying meal that everyone will love.
- Crispy Curly Fries: The crunchiness of these golden fries is the perfect contrast to the soft, gooey textures of the sandwiches, making every bite exciting.
- Fresh Side Salad: A light and colorful salad adds a refreshing touch, balancing the richness of the beef and cheese sauce with crisp greens and a zesty vinaigrette.
- Classic Coleslaw: The creamy and tangy coleslaw provides a delightful crunch, enhancing the flavor profile while offering a pleasant textural contrast.
- Homemade Potato Chips: Lightly salted, crunchy chips are ideal for dipping into any leftover cheese sauce, bringing a nostalgic snack element to your meal.
- Pickles or Pickled Vegetables: Their briny tang cuts through the richness and adds a zingy freshness, elevating your sandwich experience.
- Iced Tea or Lemonade: A chilled drink, like iced tea or lemonade, provides a refreshing counterbalance to the savory flavors, keeping your palate refreshed.
These harmonious pairings create a comforting and satisfying feast, perfect for sharing with family and friends!
Expert Tips for Hot Roast Beef Sandwiches
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Choose Fresh Cheese: Always opt for freshly shredded cheese from a block rather than pre-shredded to achieve a smooth, creamy texture in your cheddar cheese sauce.
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Thicken or Thin: If your cheese sauce becomes too thick when reheating, simply stir in a splash of milk until it reaches your desired consistency.
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Horseradish Balance: Adjust the amount of horseradish in your mayo according to your taste preference; less for a milder flavor and more for that zesty kick.
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Customize Bread: While hamburger buns are classic, feel free to switch to whole grain bread or hoagie rolls for an exciting variation that fits your dietary choices.
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Don’t Overheat Beef: Warm the deli roast beef gently; overcooking can lead to tough meat, which will detract from the overall experience of your hot roast beef sandwiches.
Hot Roast Beef Sandwiches Variations
Feel free to let your creativity shine and customize these delicious sandwiches to suit your taste buds!
- Sautéed Onions: Add caramelized onions for a sweet, savory touch that pairs wonderfully with the beef. The rich flavor elevates each bite, making your sandwiches extra special.
- Mushrooms: Including sautéed mushrooms brings an earthiness that complements the roast beef beautifully. This simple addition enhances the umami profile, offering a satisfying depth of flavor.
- Spicy Twist: Spice things up with jalapeños or use pepper jack cheese instead of cheddar. This variation adds a delightful heat that brings a fresh twist to the classic recipe.
- Healthier Options: Swap regular mayonnaise for Greek yogurt and use low-fat cheese for a lighter take. You’ll enjoy all the flavors while making a mindful choice.
- Whole Grain Bread: Replace your hamburger buns with whole grain or multi-grain bread for added fiber and a nutty flavor. It’s a nutritious choice that doesn’t compromise on taste.
- BBQ Sauce: Blend in a bit of your favorite BBQ sauce with the cheese for a smoky twist. This not only enhances the flavor profile but creates a delicious fusion of flavors reminiscent of summer cookouts.
- Herbal Infusion: Mix fresh herbs like parsley or chives into the cheese sauce for an aromatic touch. This brightens the dish and adds beautiful color and freshness.
- Cheese Variety: Mix it up by combining different cheeses like gouda or muenster with the cheddar. This delightful cheese medley can make for a mouthwatering flavor explosion!
Explore these variations, and perhaps complement your sandwiches with crispy curly fries or a zesty side salad for a well-rounded meal!
How to Store and Freeze Hot Roast Beef Sandwiches
Fridge: Store leftovers in an airtight container for up to 3 days. Keep the sandwich components separate to maintain the freshness of the ingredients.
Freezer: If you’ve prepared extra roast beef or cheese sauce, these can be stored in the freezer for up to 2 months. Ensure they’re in airtight containers or freezer bags, and thaw overnight in the fridge before reheating.
Reheating: To reheat, warm the roast beef in a skillet over low heat and microwave the cheese sauce in short intervals, stirring until smooth. Assemble the sandwiches freshly before serving.
Assembly Tip: For optimal texture, it’s best to assemble your hot roast beef sandwiches just before serving, allowing the bread to stay soft and the flavors to meld together beautifully.

Hot Roast Beef Sandwiches Recipe FAQs
What type of roast beef is best for this recipe?
Absolutely! Thin-sliced deli roast beef works perfectly for these sandwiches. If you have leftover roast beef, feel free to use that; just shred or slice it thinly to make assembly easier and ensure it warms thoroughly.
How should I store leftover hot roast beef sandwiches?
To preserve freshness, store any leftover components in separate airtight containers in the fridge for up to 3 days. This way, your sandwich ingredients remain at their best texture and flavor until you’re ready to enjoy them again!
Can I freeze the cheese sauce or roast beef?
Yes, you can freeze both the cheddar cheese sauce and the roast beef. Pack them in airtight containers or freezer bags, and they’ll keep for up to 2 months. When ready to use, thaw overnight in the fridge to maintain quality, then simply reheat as needed.
What if my cheese sauce is too thick?
If your cheese sauce thickens while reheating, don’t worry! Just add a splash of milk and stir until smooth. This helps return it to that creamy, luscious texture perfect for your sandwiches!
Are there any dietary considerations for these sandwiches?
Definitely! If you’re concerned about allergies, be mindful of the horseradish and mayonnaise; try substituting with a dairy-free yogurt for mayo. Additionally, using gluten-free buns can help make this recipe suitable for those with gluten sensitivities.
Can I customize my hot roast beef sandwiches?
Very! You can easily add sautéed onions, mushrooms, or even jalapeños for extra flavor. If you prefer a lighter option, consider using low-fat cheese and whole grain buns. The more the merrier when it comes to personalization!

Melt-in-Your-Mouth Hot Roast Beef Sandwiches at Home
Ingredients
Equipment
Method
- Prepare the Horseradish Mayo: In a small bowl, combine creamy horseradish with mayonnaise, mixing thoroughly until smooth.
- Make the Cheddar Cheese Sauce: Toss the shredded mild cheddar cheese with cornstarch, then gradually whisk in evaporated milk, and heat in the microwave.
- Warm the Roast Beef: Heat a skillet over medium heat, melt the butter, and add the thin-sliced deli roast beef, warming thoroughly.
- Assemble the Sandwiches: Spread horseradish mayo on the bottom halves of the buns, layer with warm roast beef, and top with cheddar cheese sauce.
- Serve and Enjoy: Serve the sandwiches immediately, optionally with crispy curly fries or a fresh side salad.

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